A nuclear (fission-fusion) bomb takes about 600ns to detonate. In that time, a 2Ghz Intel Core Duo can execute about 2400 instructions. (Crudely: 2 instructions per cycle x 2 billion cycles per second x .000000001 seconds per ns x 600ns = 2400 instructions.)
Worth pointing out: According to wiki, the plasma compression method cited in the above linked article’s graphic is now thought to be of only minor importance; tamper ablation is now thought to be the dominant mechanism for secondary compression. (In other words, spend a few minutes reading about the Teller-Ulam design. It’s fascinating.)